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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKDC
All Species:
19.09
Human Site:
S543
Identified Species:
46.67
UniProt:
P78527
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78527
NP_001075109.1
4128
469089
S543
S
S
D
Q
M
M
D
S
I
L
A
D
E
A
F
Chimpanzee
Pan troglodytes
XP_001147162
4128
468882
S543
S
S
D
Q
M
M
D
S
I
L
A
D
E
A
F
Rhesus Macaque
Macaca mulatta
XP_001100610
4128
469402
S543
T
S
D
Q
M
M
D
S
I
L
A
D
E
A
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97313
4128
471369
F543
G
C
D
Q
M
E
D
F
I
L
G
D
E
T
F
Rat
Rattus norvegicus
NP_001101797
2098
241314
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514950
4153
474137
S565
N
C
D
E
M
K
D
S
Q
L
D
E
T
F
L
Chicken
Gallus gallus
Q8QGX4
4134
472639
S540
S
C
D
T
M
K
E
S
I
F
E
E
E
N
F
Frog
Xenopus laevis
Q9DEI1
4146
473487
S565
R
C
D
Q
L
K
D
S
I
F
S
D
E
I
F
Zebra Danio
Brachydanio rerio
XP_001919588
4119
467204
T548
D
C
E
N
L
K
D
T
G
F
V
D
G
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781813
1817
205237
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.5
N.A.
N.A.
79.1
39.2
N.A.
74.1
68.8
64
58.5
N.A.
N.A.
N.A.
N.A.
20.8
Protein Similarity:
100
99.8
98.8
N.A.
N.A.
88.7
44.7
N.A.
85.4
82.5
79.8
76.1
N.A.
N.A.
N.A.
N.A.
31.6
P-Site Identity:
100
100
93.3
N.A.
N.A.
60
0
N.A.
33.3
46.6
53.3
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
N.A.
N.A.
60
0
N.A.
53.3
60
66.6
40
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
30
0
0
40
0
% A
% Cys:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
70
0
0
0
70
0
0
0
10
60
0
0
0
% D
% Glu:
0
0
10
10
0
10
10
0
0
0
10
20
60
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
30
0
0
0
10
60
% F
% Gly:
10
0
0
0
0
0
0
0
10
0
10
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
60
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
40
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
20
0
0
0
0
50
0
0
0
0
10
% L
% Met:
0
0
0
0
60
30
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
50
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
30
30
0
0
0
0
0
60
0
0
10
0
0
0
0
% S
% Thr:
10
0
0
10
0
0
0
10
0
0
0
0
10
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _